Selective 5-HT 1A receptor agonist that displays high intrinsic activity (K i values are 0.4, 7.7 and 36 nM for 5-HT 1A , 5-HT 1D and D 2 receptors respectively and > 1000 nM for 5-HT 2 , D 1 , α 1 and α 2 receptors). Produces hypothermia, hypotension and 5-HT behavioral syndrome following p.o. administration.
