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3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine hydrochloride
Product Name
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine hydrochloride
CAS
MF
C11H9ClN2S
MW
236.72056
EINECS
MOL File
Mol File
Usage And Synthesis
Biological Activity
Potent, selective and non-competitive mGlu 5 antagonist (IC 50 = 5 nM in Ca 2+ -flux assay; K i = 16 nM). Displays anxiolytic activity in vivo and is orally active.
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![3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine hydrochloride Structure](/CAS/20200119/GIF/CB32134911.gif)