LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4; IC50 = 0.38 µM).1 It is selective for ACSL4 over ACSL3 (IC50 = >50 µM) and peroxisome proliferator-activated receptor γ (PPARγ; IC50 = >10 µM).WARNING This product is not for human or veterinary use.
References
[1] DARIUS MAZHARI DOROOEE. LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode[J]. Angewandte Chemie International Edition, 2025, 64 19. DOI: 10.1002/anie.202500518
