Cholic Acid 3-sulfate (potassium salt)

Cholic acid 3-sulfate is a metabolite of the primary bile acid cholic acid (Item No. 20250).1,2 Plasma levels of cholic acid 3-sulfate are increased in patients with intrahepatic cholestasis and mutations in the gene encoding the bile salt export pump (BSEP), ABCB11.3WARNING This product is not for human or veterinary use.

[1] ALNOUTI Y. Bile Acid sulfation: a pathway of bile acid elimination and detoxification.[J]. Toxicological Sciences, 2009, 1 1: 225-246. DOI: 10.1093/toxsci/kfn268
[2] J GOTO. Studies on steroids. CLXX. Separation and determination of bile acid 3-sulfates in human bile by high-performance liquid chromatography.[J]. Journal of chromatography, 1981, 226 1: 13-24.
[3] TENG LIU. Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations[J]. Liver International, 2018, 38 9: 1676-1685. DOI: 10.1111/liv.13714