N-单甲基-L-精氨酸单乙酸酯
N-单甲基-L-精氨酸单乙酸酯 性质
| 熔点 | 180-190 °C |
|---|---|
| 比旋光度 | D22 +9.5° (c = 0.10 in water) |
| 沸点 | 391.35°C (rough estimate) |
| 密度 | 1.2162 (rough estimate) |
| 折射率 | 1.6300 (estimate) |
| 储存条件 | 2-8°C |
| 溶解度 | H2O：1 mg/mL，澄清，无色 |
| 形态 | 粉末 |
| 颜色 | 白色至类白色 |
| 水溶解性 | Soluble in water (50 mM) |
| BRN | 6674255 |
| 稳定性 | -5°C储存；保持干燥 |
| InChIKey | IKPNWIGTWUZCKM-JEDNCBNOSA-N |
N-单甲基-L-精氨酸单乙酸酯 用途与合成方法
Ki: 0.18 µM (nNOS), 0.4 µM (eNOS), 6 µM (iNOS)
L-NMMA, starting from 100 μM, produces a concentration-dependent inhibition of the evoked relaxations (2Hz); maximal inhibition at 1 mM averaged about 35%. The inhibitory effect of L-NMMA is unchanged by previous incubation with D-arginine while it is prevented by L-arginine (L-Arg). L-NMMA does not affect isoprenaline-induced relaxation. Superfusion of L-NMMA reduces arteriolar diameter and causes dose-dependent increases in arteriolar tone. The onset of action of L-NMMA is nearly immediate. L-NMMA inhibits vasodilator responses to the endothelium-dependent vasodilator ACh but not to the endothelium-independent NP. NE induced dose-related vasoconstriction that is significantly potentiated by L-NMMA.
N-单甲基-L-精氨酸单乙酸酯 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | 32872 | NG—单甲基—L—精氨酸醋酸盐 100MG | 53308-83-1 | 5mg | 607 |
| 2024-11-08 | 32872 | NG—单甲基—L—精氨酸醋酸盐 100MG | 53308-83-1 | 25mg | 1744 |
