8-BROMO-ATP
中文名称:8-BROMO-ATP
英文名称:8-bromoadenosine 5'-triphosphate
CAS号:23567-97-7
分子式:C10H15BrN5O13P3
分子量:586.08
EINECS号:
Mol文件:23567-97-7.mol
8-BROMO-ATP 性质
| 沸点 | 983.1±75.0 °C(Predicted) |
|---|---|
| 密度 | 2.85±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 0.97±0.50(Predicted) |
8-BROMO-ATP 用途与合成方法
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate)，一种 ATP 类似物，是一种嘌呤能 P2X receptor 受体的激动剂。8-Bromo-ATP 对多发性骨髓瘤细胞具有细胞毒性，IC50 为 23.1 μM。
8-Bromo-ATP (10-50 μM; 5 days) treatment shows cytotoxic to multiple myeloma.
Fluorescence measurements are made possible through the use of 8-Bromo-ATP, which selectively quenched certain tryptophan residues of the ATPase. 8-Bromo-ATP enhances the rate of dephosphorylation of native ATPase 2-3-fold when added in the absence of divalent cations.
Cell Viability Assay
| Cell Line: | MM 1.s cells |
| Concentration: | 10 μM, 20 μM, 30 μM, 40 μM, 50 μM |
| Incubation Time: | 5 days |
| Result: | Showed cytotoxic to multiple myeloma. |
8-BROMO-ATP供应商 更多
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产品介绍：
英文名称：8-Bromo-ATP
CAS：23567-97-7
纯度：详情请点击官网
包装信息：1 mg
备注：试剂级
