Sabeluzole (5 mg/kg, 25 mg/kg; sc; twice dose with 72 h interval) shows positive and memory enhancing properties in habituation amnesia male rats induced with 20 mg/kg Chlordiazepoxide[2].
| Animal Model: | Adult albino male rats (270-330 g) induced by Chlordiazepoxide[2] |
| Dosage: | 5 mg/kg, 25 mg/kg |
| Administration: | SC; 0.5 ml/kg; twice dose with 72 h interval; 1 h before 20 mg/kg Chlordiazepoxide |
| Result: | Showed the positive effects on several learning and memory tasks in rats.
Did not influence locomotor and rearing activity of animals during the acquisition session. |
