Γ-D-谷氨酰基甘氨酸
Γ-D-谷氨酰基甘氨酸 性质
| 熔点 | ～191℃ |
|---|---|
| 沸点 | 586.6±50.0 °C(Predicted) |
| 密度 | 1.424±0.06 g/cm3(Predicted) |
| 储存条件 | -15°C |
| 溶解度 | 水：85.21（最大浓度 mg/mL）；417.32（最大浓度 mM） |
| 酸度系数(pKa) | 2.21±0.10(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至米白色 |
Γ-D-谷氨酰基甘氨酸 用途与合成方法
AMPA receptor
gamma-DGG (γ-DGG), a competitive AMPA receptor blocker that blocks less at higher glutamate concentration. At 200-400 μM, gamma-DGG in the bath reduces the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses), and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left. gamma-DGG (γ-DGG) is the most effective antagonist of the excitatory post-synaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p. Quantal analysis shows that the reduction in the e.p.s.p. paralleled the decrease in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG.
Γ-D-谷氨酰基甘氨酸 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-100785 | Γ-D-谷氨酰基甘氨酸 | 6729-55-1 | 5mg | 500 |
| 2024-11-08 | HY-100785 | Γ-D-谷氨酰基甘氨酸 | 6729-55-1 | 10mM * 1mLin Water | 550 |
