Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner[2].
Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption[1].
| Animal Model: | Male Sprague-dawley rats (200-280g)[2] |
| Dosage: | 2, 5, 10 mg/kg |
| Administration: | IP |
| Result: | Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.
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