基本属性 生物活性靶点体内研究 用途与合成方法 BETA- AMYLOID (1-16) 价格(试剂级) 供应商 供应信息 相关产品
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BETA- AMYLOID (1-16)

BETA- AMYLOID (1-16)

英文名称:H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH
CAS号:131580-10-4
分子式:C84H119N27O28
分子量:1955.01
EINECS号:
Mol文件:131580-10-4.mol
BETA- AMYLOID (1-16) 结构式

BETA- AMYLOID (1-16) 性质

密度 1.57±0.1 g/cm3(Predicted)
储存条件 -15°C
溶解度 溶于二甲基亚砜
形态 固体
颜色 白色至米白色
水溶解性 Soluble in water or aqueous buffer
序列 H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH

BETA- AMYLOID (1-16) 用途与合成方法

β-Amyloid (1-16) 是可参与金属结合的β-淀粉样蛋白片段。 β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。

Amyloid-β

β-amyloid (1-16) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu 2+ interaction. Oxidation targets for β-Amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with β-Amyloid (1-16) taking part in the coordination of the Cu 2+ ions. Cu 2+ and Zn 2+ are linked with the neurotoxicity of -Amyloid and free radical damage. β-amyloid (1-16) is the minimal amino acidic sequence display a Cu coordination mode which involves three Histidines (His6, His13 and His14). β-amyloid (1-16) is supposed to be involved in metal binding. Human β-amyloid interacts with zinc ions through its metal-binding domain 1-16. The C-tails of the two polypeptide chains of the rat Aβ(1-16) dimer are oriented in opposite directions to each other, which hinders the assembly of rat Aβ dimers into oligomeric aggregates. Thus, the differences in the structure of zinc-binding sites of human and rat β-Amyloid (1-16), their ability to form regular cross-monomer bonds, and the orientation of their hydrophobic C-tails could be responsible for the resistance of rats to Alzheimer's disease.

参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量5.0%~12.0%
水分含量≤8.0%
肽含量≥80.0%

BETA- AMYLOID (1-16) 价格(试剂级)

更新日期 产品编号 产品名称 CAS号 包装 价格
2024-11-08 HY-P1466 BETA- AMYLOID (1-16) 131580-10-4 1mg 1100
2024-11-08 HY-P1466 BETA- AMYLOID (1-16) 131580-10-4 5mg 3900

BETA- AMYLOID (1-16)供应商 更多

上海鸿肽生物科技有限公司
现货
联系电话: 19961912513
产品介绍:
中文名称:β-淀粉样蛋白 Amyloid β-Protein (1-16)
英文名称:Amyloid β-Protein (1-16)/β-Amyloid (1-16), human
CAS:131580-10-4
纯度:99% HPLC MS
包装信息:1mg;5mg;10mg;100mg;500mg;1kg;5kg;25kg
备注:科研级
库存量:1kg
现货日期:2024/11/24 21:25:35
吉尔生化(上海)有限公司
联系电话:21-61263452 13641803416
产品介绍:
英文名称:Beta-Amyloid (1-16);DAEFRHDSGYEVHHQK
CAS:131580-10-4
纯度:95% HPLC 98% HPLC
包装信息:1mg,5mg,10mg,25mg,100mg,1g,10g
上海瀚鸿科技股份有限公司
联系电话:021-54306202 13764082696
产品介绍:
英文名称:Amyloid β-Protein (1-16)
CAS:131580-10-4
备注:332P2161
合肥赛曼诺生物科技有限公司
联系电话:0551-65326643 18156095617
产品介绍:
英文名称:AMyloid β-Protein (1-16)
CAS:131580-10-4
纯度:98% HPLC
包装信息:5Mg;10Mg;1g
北京索莱宝科技有限公司
联系电话:010-50973130 4009686088
产品介绍:
英文名称:Beta-Amyloid (1-16)

最新发布供应信息

β-淀粉样蛋白 Amyloid β-Protein (1-16)
绍兴市均宇生物科技有限公司 2024-11-26
β-淀粉样蛋白 Amyloid β-Protein (1-16)
杭州固拓生物科技有限公司 2024-11-25

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