Anti-Cholera Toxin, B-Subunit(Goat)

Anti-cholera toxin B subunit (goat) is a polyclonal anti-choleragenoid from goat that is suitable for use in toxin neutralization and binding assays or for immunohistochemical studies in conjunction with the cholera toxin B subunit. The pentameric B subunit of cholera toxin (Item No. 19654) binds with high efficiency to GM1 monosialoganglioside cell membrane receptors found on mammalian cell surfaces and facilitates entrance of the A subunit into cells.1 The cholera toxin B subunit is often used for retrograde track tracing studies in neuroscience research.2WARNING This product is not for human or veterinary use.

[1] JIN A CHO. Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins.[J]. Frontiers in Cellular and Infection Microbiology, 2012: 51. DOI: 10.3389/fcimb.2012.00051
[2] KEEGAN J BALDAUF. Cholera toxin B: one subunit with many pharmaceutical applications.[J]. Toxins, 2015, 7 3: 974-996. DOI: 10.3390/toxins7030974