L-Valine, N-[[1-(5-fluoropentyl)-1H-indazol-3-yl]carbonyl]-, ethyl ester

AB-PINACA is a synthetic cannabinoid identified in illegal herbal products.¹ Variations of AB-PINACA have been synthesized including derivatives that include a fluorine atom added to the terminal carbon of the pentyl group. 5-fluoro AEB is an analog of AB-PINACA characterized by the replacement of the carboxamide with ethyl acetate and the addition of an alkyl-terminal fluorine atom. The physiological and toxicological properties of this compound have not been determined. 5-fluoro AEB is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

1. Uchiyama, N., Matsuda, S., Wakana, D., et al. New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products Forensic Toxicol. 31(1),93-100(2013).