U-62066 (SPIRADOLINE MESYLATE) K-OPIOID AGONIST

Chemical Properties

Boiling point	563.070±50.00 °C(Press: 760.00 Torr)(predicted)
Density	1.272±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.	2-8°C
solubility	H2O: soluble14mg/mL
form	solid
pka	9.144±0.20(predicted)
color	white
Water Solubility	H2O: 14mg/mL methanol: insoluble
InChIKey	FHEZDPDAYTVKKG-JLBKCEDKSA-N
SMILES	CS(O)(=O)=O.CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N3CCCC3)C(=O)Cc4ccc(Cl)c(Cl)c4

WGK Germany	3
Storage Class	11 - Combustible Solids

Animal Model:	Juvenile, adolescent and adult Sprague-Dawley male and female rats exposured to repeated restraint^[1]
Dosage:	0.1 mg/kg, 0.2 mg/kg, 0.3 mg/kg, and 0.4mg/kg
Administration:	Subcutaneous injection; once
Result:	Dose-dependently reduced social behaviors in non-stressed adults, producing social avoidance at the highest dose tested.