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ergotamine

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ergotamine Basic information
ergotamine Chemical Properties
  • Melting point:241-249℃
  • alpha D20 -160° (chloroform)
  • Boiling point:651.33°C (rough estimate)
  • Density 1.0998 (rough estimate)
  • refractive index 1.7500 (estimate)
  • pkapKa 6.40±0.09(H2O t=24.0) (Uncertain)
  • CAS DataBase Reference113-15-5
Safety Information
  • RIDADR 1544
  • HazardClass 6.1(b)
  • PackingGroup III
  • ToxicityLD50 in mice, rats, rabbits (mg/kg): 62, 80, 3 i.v.; in cats: 11 s.c. (Rothlin)
ergotamine Usage And Synthesis
  • UsesAnalgesic (specific in migraine).
  • DefinitionChEBI: A peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10.
  • brand nameErgomar (Harvest);Ergostat (Parke-Davis); Wigrettes (Organon).
  • Purification MethodsCrystallise it from *benzene, then dry it by prolonged heating in high vacuum. It is very hygroscopic. [Beilstein 25 III/IV 964.]
ergotamine (113-15-5)Related Product Information
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