Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. Terlipressin is used norepinephrine-resistant septic shock and hepatorenal syndrome. Terlipressin is also used in the treatment of acute variceal bleeding.
in vivo
Using a mouse nonlethal hepatic ischemia-reperfusion (IR) model, Terlipressin diacetate administration significantly ameliorates IR-induced liver apoptosis, necrosis and inflammation[3].
