Oxantel (1-10 mg/kg; i.p.) displays a high activity against T. muris in vivo, with an EC50 of 4.71 mg/kg[1].
Oxantel (10 mg/kg; i.p.) exhibits a worm burden reduction (WBR) of 92.5% and worm expulsion rate (WER) of 88.4% for T. muris[1].
| Animal Model: | 4 week-old female C57BL/10 mice and 3 week-old male[1] |
| Dosage: | 1 mg/kg, 2.5 mg/kg, 5 mg/kg, 10 mg/kg |
| Administration: | Intraperitoneal injection |
| Result: | Inhibited T. muris in vivo. |
