The gene IGFBP-6 (insulin-like growth factor binding protein-6) is mapped to human chromosome 12q13.
IGFBP-6 (insulin-like growth factor binding protein-6) works as a tumor suppressor for nasopharyngeal carcinoma and also suppresses prostate cancer cell proliferation.', 'Insulin-like growth factor binding protein found in cerebrospinal fluid and serum; exhibits 2-fold higher affinity for IGF-II than for IGF-I.
IGFBP6 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing amino acids 148-240 and having a molecular mass of 20 kDa including 4kDa His tag.
IGFBP6 is purified by proprietary chromatographic techniques.
IGFBP6 plays a role in lipoprotein assembly and dietary cholesterol absorption. in addition to its acyltransferase activity, it may act as a ligase. may provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
