5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE

CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines.

ChEBI: 5,6-bis(4-fluoroanilino)isoindole-1,3-dione is a member of phthalimides.

Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro .

Store at RT