Monoclonal Anti-CYGB antibody produced in mouse

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Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002 [PubMed 11893755]).[supplied by OMIM

Cytoglobin (CYGB) is down-regulated in tylosis with oesophageal cancer (TOC). The protein′s heme co-ordination changes based on the lipids present in the surroundings and this in turn transforms the redox properties of the protein. CYGB may act as a marker to differentiate groups of cells in a damaged liver.