Pentapeptide 18, also called leuphasyl, limits catecholamine and acetylcholine release by mimicking the
effects of enekphalin on the extracellular encephalin receptors of nerve cells. The subsequent activation
of inhibitory G protein coupled receptors results in a decrease of the neuronal cell’s excitability and the
prevention of neurotransmitter release. In vitro studies have shown this effect on glutamate from neurons.
One active controlled trial compared 5% leuphasyl solution to 5% argireline and a combination of
5% leuphasyl and 5% argireline. This study showed comparable effects of these two drugs on wrinkles
when used singly, and when used together, they resulted in a synergistic and more powerful reduction
of wrinkles.
Pentapeptide-3 is a synthetic peptide containing alanine, arginine, isoleucine, glycine and proline
Pentapeptide-3 is super anti-wrinkle multi-peptide with various kindof peptides, working by different targets to powerfulyinhibit the muscle contraction, instantly reduce theexpression lines, e.g. frown lines, laughter lines andcrows feet lines, etc., safer and milder replacementcompare to botox.Winkey patented product in China.Its recommended dosage is 3~10%.
