Reference standard in the analysis of herbal medicinal products.
Hepatoprotectant. In nature, the flavonolignan Silybin occurs as a mixture of two diastereomers, Silybin A and Silybin B.
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Exact content by quantitative NMR can be found on the certificate.
Silybin (50, 100mg/kg/day; given intragastrically for the last 4 weeks) significantly lowers both serum and hepatic lipid accumulation[2].
| Animal Model: | Male C57BL/6J mice (6-8 weeks old) with nonalcoholic fatty liver disease (NAFLD)[2] |
| Dosage: | 50, 100mg/kg |
| Administration: | Given intragastrically; daily; for the last 4 weeks |
| Result: | Significantly lowered both serum and hepatic lipid accumulation.
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