ChEBI: Cinanserin hydrochloride is the hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro. It has a role as an antiviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an anticoronaviral agent. It contains a cinanserin(1+).
Cinanserin Hydrochloride is a useful research chemical. Cinanserin is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
Cinanserin (5 mg/kg; intravenous injection; for 2 hours; male Wistar rats) treatment significantly reduces systemic burn edema to shamburn levels. Leukocyte-endothelial interactions are significantly reduced by administration of Cinanserin[2].
| Animal Model: | Male Wistar rats (250 g) underwent thermal injury[2] |
| Dosage: | 5 mg/kg |
| Administration: | Intravenous injection; for 2 hours |
| Result: | Significantly reduced systemic burn edema to shamburn levels..
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5-HT2 Receptor: 41 nM (Ki); 3C-like proteinase
