OAC2
OAC2 性质
熔点 | 165 - 167°C |
---|---|
沸点 | 364.3±15.0 °C(Predicted) |
密度 | 1.307±0.06 g/cm3(Predicted) |
储存条件 | Sealed in dry,Room Temperature |
溶解度 | 可溶于DMSO(少许)、甲醇(少许) |
酸度系数(pKa) | 13.99±0.43(Predicted) |
形态 | 固体 |
颜色 | 淡黄色低 |
OAC2 用途与合成方法
Target | Value |
OCT4
() |
Octamer-binding transcription factor 4 (Oct4) is a master regulator of the induction and maintenance of cellular pluripotency, and has crucial roles in early stages of differentiation. It is the only factor that cannot be substituted by other members of the same protein family to induce pluripotency. Oct4 has been shown to be an essential regulator of embryonic stem cell (ESC) pluripotency and key to the reprogramming process. OAC2 is a structural analog of OAC1. OAC2 activates both Oct4 and Nanog reporters to a similar extent as OAC1. OAC1 and its two structural analogs OAC2 and OAC3 enhances reprogramming efficiency fourfold, up to as high as 2.75%, and accelerates the appearance of iPSC colonies 3 to 4 d when used in combination with the four reprogramming factors, Oct4, Sox2, Klf4, and c-Myc.
OAC2 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2025-02-05 | HY-12884 | 6019-39-2 | 5 mg | 337 | |
2025-02-05 | HY-12884 | OAC2 | 6019-39-2 | 10mM * 1mLin DMSO | 370 |