(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) 性质
储存条件 | Store at -20°C |
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溶解度 | 在 10% 乙腈中溶解度为 1 mg/ml |
形态 | 粉末 |
颜色 | 白色至米白色 |
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) 用途与合成方法
hY 5 receptor 0.24 nM (IC 50 ) |
hY 1 receptor 530 nM (IC 50 ) |
hY 2 receptor >500 nM (IC 50 ) |
hY 4 receptor 51 nM (IC 50 ) |
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide has IC 50 s of 530 nM, >500 nM, 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors.
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide (0.2, 2 nmol/rat) induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g.