1,2-Epoxyhexane is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.
1,2-Epoxyhexane could used as a passivating agent for core–shell aluminum nanoparticles with very high active aluminum content[1].
A method for preparing 1,2-epoxyhexane using a fixed-bed microchannel reaction device is as follows: dissolve 1-hexene in a solvent to prepare a 1-hexene solution, and then dissolve an oxidizing reagent in the solvent to prepare an oxidizing reagent solution. Add the solid catalyst into the fixed-bed microchannel reaction device. Pump the 1-hexene and oxidizing reagent solution configured above into the fixed-bed microchannel reaction device respectively, maintain the reaction residence time for 8-25 minutes, and the upper organic phase enters the continuous centrifuge. The product is obtained after continuous water washing.
Keep container tightly closed. Store away from oxidizing agents.
Purify it by fractional distillation through a 2ft helices-packed column at atmospheric pressure in a N2 atmosphere. [Pasto & Cumbo J Org Chem 30 1271 1965, Howarth et al. J Chem Soc 2433 1927, 13C NMR Davies & Witham J Chem Soc Perkin Trans 2 861 1975, Beilstein 17/1 V 103.]
[1] Paul A. Jelliss . “The use of 1,2-epoxyhexane as a passivating agent for core–shell aluminum nanoparticles with very high active aluminum content.” Solid State Sciences 23 (2013): Pages 8-12.
