6-Benzyloxyindole

• Reactant for enantioselective synthesis of quaternary carbon-containing 3-(3-indolyl)isoindolin-1-ones
• Reactant for Friedel-Crafts alkylation reactions with hydroxyisoindolinones
• Reactant for direct and regioselective synthesis of β-heteroarylated ketones
• Reactant for preparation of hepatitis C virus (HCV) inhibitors
• Reactant for preparation of protein kinase C (PKC) inhibitors
• Reactant for preparation of indol-3-yl tetramethylcyclopropyl ketones as CB2 cannabinoid receptor ligands

153805-86-8

2380-86-1

15903-94-3

The compound (CAS: 153805-86-8) was used as starting material and synthesized by a method similar to Example 32. The specific operation was as follows: 5% rhodium/carbon powder was added to the reaction system as a catalyst, and the metal compounds ferrous acetate (II), nickel nitrate (II) or cobalt acetylacetonate (III) were introduced as co-catalysts. 5-Benzyloxy-2-(2-pyrrolidinylvinyl)nitrobenzene was used as the substrate for the reduction reaction. Upon completion of the reaction, as shown in Table 6, the yield of 6-benzyloxyindole was significantly increased and the by-product yield of 6-hydroxyindole was decreased when the reducing agent of the present invention was used as compared to the counterpart 5.