SPDP acid contains SPDP and carboxylic acid moieties. The SPDP react with amine and thiol groups and are commonly used in the crosslinking of proteins. The carboxylic acid can react with primary amines in the presence of EDC and HATU, to form stable amide bonds.
Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis.
Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes
osphated bovine serum albumin for treatment of liver fibrosis.
