(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
英文名称:(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
CAS号:29734-68-7
分子式:C16H21NO3.BrH
分子量:356.25
EINECS号:
Mol文件:29734-68-7.mol
![(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE 结构式](https://img.chemicalbook.com/CAS/GIF/29734-68-7.gif)
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE 性质
| 储存条件 | Desiccate at RT |
|---|---|
| 溶解度 | 乙醇：5mg/mL |
| 形态 | 固体 |
| 熔点 | 219-229 °C (decomp) |
| 颜色 | 白色 |
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE 用途与合成方法
Dihydro-β-erythroidine (DHβE) hydrobromide 是一种有效竞争性的，具有口服活性的神经 nAChRs 拮抗剂。Dihydro-β-erythroidine hydrobromide 对 α4β4 和 α4β2 有选择性，IC50 分别为 0.19 和 0.37 μM。具有抗抑郁类活性。
Dihydro-Beta-Erythroidine hydrobromide (DHβE hydrobromide; 10 nmol/0.5 μL) is infused into the respective areas prior to a systemic nicotine injection (0.2 mg/kg; SC). DHβE infused into the ventral tegmental area (VTA), nucleus accumbens (NAcc), or infralimbic (IL) cortex, but not prelimbic (PrL) cortex, attenuated nicotine-enhanced responding for a conditioned reinforcer (CRf).
The co-administration of Dihydro-Beta-Erythroidine hydrobromide (5.0 mg/kg; s.c) with nicotine (0.2 and 0.4 mg/kg; s.c.) prevents the development of conditioned taste aversions (CTAs).
| Animal Model: | Male hooded Lister rats |
| Dosage: | 0.5, 1.6 and 5.0 mg/kg |
| Administration: | S.c. |
| Result: | A complete blockade of the nicotine effect produced by the training dose of nicotine (0.2 mg/kg). |
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-08-19 | HY-107670 | 1 mg | 1840 | ||
| 2024-08-19 | HY-107670 | (2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE | 29734-68-7 | 5mg | 4050 |
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE供应商 更多
武汉易泰科技有限公司上海分公司
联系电话：821-50328103-801 18930552037
产品介绍：
英文名称：Dihydro-β-erythroidine hydrobroMide;(2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-onehydrobroMide
CAS：29734-68-7
纯度：99% HPLC
包装信息：1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
MedBio脉铂医药
联系电话：021-69568360 18916172912
产品介绍：
英文名称：(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
CAS：29734-68-7
纯度：98%
包装信息：50mg; 10mg
备注：Medbio
天津普西唐生物医药科技有限公司
联系电话：010-60605840 15801484223;
产品介绍：
英文名称：Dihydro-β-erythroidine hydrobromide
CAS：29734-68-7
纯度：98%
包装信息：5mg;10mg
上海优宁维生物科技股份有限公司
联系电话： 18768175414
产品介绍：
英文名称：Dihydro-b-erythroidi
CAS：29734-68-7
包装信息：10mg
备注： 见优宁维官网
TargetMol中国（陶术生物）
联系电话： 4008200310
产品介绍：
中文名称：化合物 T11041
英文名称：Dihydro-β-erythroidine hydrobromide;Dihydroβerythroidine hydrobromide,Dihydro β erythroidine hydrobromide
CAS：29734-68-7
纯度：98%
包装信息：25 mg
