hydantocidin

Hydantocidin (52), a microbial spironucleoside, selectively inhibits plant adenylsuccinate synthetase only after in vivo phosphorylation, resulting in the 5 -monophosphate 52, an analog of adenosine 5 -monophosphate (74) .

Hydantocidin is an adenylosuccinate synthetase inhibitor and a spiroribofuranose. Hydantocidin can be produced by Streptomyces hygroscopicus. Hydantocidin has strong herbicidal activity toward annual, biennial and perennial weeds[1].

[1] Shiozaki M. Synthesis of hydantocidin and C-2-thioxo-hydantocidin. Carbohydr Res. 2001 Oct 8;335(3):147-50. DOI:10.1016/s0008-6215(01)00239-7