十六碳烯酸
十六碳烯酸 性质
| 沸点 | 369.8±11.0 °C(Predicted) |
|---|---|
| 密度 | 0.905±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 氯仿：可溶；乙醇：可溶；乙醚：可溶；甲醇：可溶 |
| 酸度系数(pKa) | 4.75±0.10(Predicted) |
十六碳烯酸 用途与合成方法
MBC: 31.3 μg/mL ( Streptococcus sanguinis ), 375.0 μg/mL ( Streptococcus mitis ) and 93.8 μg/mL ( Fusobacterium nucleatum )
Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis , Streptococcus mitis , and Fusobacterium nucleatum but not active against Escherichia coli , Staphylococcus aureus , S. marcescens , P. aeruginosa , Corynebacterium bovis , Corynebacterium striatum , and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h.
