Glucosylrutin

Glucosylrutin is a type of polyphenolic flavonoid that possesses antioxidant properties. It can inhibit reactive oxygen species-mediated chain reactions, which play a role in the development of chronic illnesses such as cardiovascular disease and cancer. Glucosylrutin has also been found to have positive effects on skin cells by inhibiting protein synthesis and the production of reactive oxygen species. It has been shown to inhibit mitochondrial membrane potential and increase the levels of intracellular Ca2+, resulting in improved functioning of the renal proximal tubules. Clinical studies have demonstrated the impact of glucosylation on alleviating symptoms in patients with chronic kidney disease, specifically those related to proximal tubular dysfunction. Additionally, glucosylrutin is beneficial for primary keratinocytes and could potentially be used for intubation treatment.

Anti-aging: eye cream, night cream, serum, mask.
Anti-allergy: skin care lotion, serum, mask.
Sunscreen: lotion, prevent sunburn, repair after sunburn.

Glucosylrutin is a chemically modified flavonoid derived from plant extracts that absorbs or blocks ultraviolet radiation and exhibits antioxidant properties. Glucosylrutin is utilized as an inner aqueous phase component in multiple emulsions for sun protection[1]. Glucosylrutin is employed as a positive control in cell viability, antioxidant, and cytokine production assays[2].

[1] Li, J., Luo, H., Huang, K., Fu, X. (2025). Synergistic sun protection via glucosylrutin-enhanced multiple emulsions. Materials Letters, 379, 137644. https://doi.org/10.1016/j.matlet.2024.137644
[2] Choi, Y.-S., Park, S.-H., Jung, I., Park, E.-J., Hong, W., Shin, J.-H., Seo, W.-S., Lee, J. (2025). Photoprotective Effects of Quercetin and Hesperidin in Polymorphous Light Eruption: A Comparative Study with Alpha-Glucosylrutin. Current Issues in Molecular Biology, 47(7), 567. https://doi.org/10.3390/cimb47070567