To a solution of 1 kg (7 moles) of 2-amino-5-nitrothiazole in 5 L of pyridine
(dried with potassium hydroxide) was added dropwise for 2-3 hours 8.5 moles
of 2-thienoylchloride. N-(5-Nitro-2-thiazolyl)-2-thiophenecarboxamide was
prepared as a yellow crystals with melting point 255-256°C.
