2-Pyridinamine, 4-(difluoromethyl)-5-[4-[(3R,5S)-3,5-dimethyl-4-morpholinyl]-6-[(3R)-3-methyl-4-morpholinyl]-1,3,5-triazin-2-yl]-

Chemical Properties

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Animal Model:	BALB/c nude female mice, Tsc1^GFAP CKO mice model^[2]
Dosage:	10 mg/kg, 25 mg/kg, 50 mg/kg
Administration:	Oral administration, twice a day, for 90 days
Result:	Significantly reduced the loss of Tsc1-induced mortality.

Animal Model:	Female C57BL/6J Mice^[1]
Dosage:	10 mg/kg (Pharmacokinetic Analysis)
Administration:	Oral administration, daily, for 4 days
Result:	C_max (1096 ng/mL), T_1/2 (3.0 h).