N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE

Y-27152, is a prodrug of the Kir6 (KATP) channel opener. It has also shown to produce antihypertensive effects in vivo, with minimal tachycardia following oral administration in hypertensive animals.

ChEBI: N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-N-phenylmethoxyacetamide is a 1-benzopyran.

Prodrug of the K ATP channel opener Y-26763 (N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide ). Inactive in vitro ; fails to modify tension in contracted aortic rings at concentrations up to 1 mM. In vivo, produces long-lasting antihypertensive effects with minimal tachycardia following oral administration in hypertensive animals.