Hop-22(29)-en-3-one can be useful in the study of chemical composition and antioxidant activity of volatiles from Patrinia Villosa obtained by optimized supercritical fluid extraction.
in vivo
3-Oxo-hop-22(29)-ene (0.31 μmol/ear; application; once) decreases 17.50 % the inflammation of mouse ear edema model[1].
Animal Model:
Adult male CD-1 mice (25-30 g) (Mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA))[1]
Dosage:
0.31 μmol/ear
Administration:
Apply to both faces of the right ear; once
Result:
Decreased 17.50% the inflammation of mouse ear edema model.