2-Chlororesorcinol

In a dry round-bottomed flask containing anhydrous aluminum trichloride (2. 6 g, 20 mmol) and resorcinol (1. 1 g, 10 mmol), 30 mL of methylene chloride was added. Dichloromethane, seal the mouth of the flask with a rubber stopper equipped with a nitrogen balloon, and add phosphorous trichloride (0. 72 ml, 10 mmol) through the rubber stopper with a syringe under an ice bath, controlling the addition time to about 90 minutes. minutes. The reaction was carried out in an ice bath with stirring for 5 h. The reaction was traced by TLC, and the unfolding agent (dichloromethane methanol=97 3/v/v/v) was observed under a UV lamp at 254 nm . The reaction was stopped and the solution was spun dry. The reaction was stopped, the solution was spun dry, 15 mL of 2N hydrochloric acid was added under an ice bath, and 200 mL of ethyl acetate was added . The organic layer was dried with anhydrous magnesium sulfate and filtered, then spun-dried to give a light yellow solid, which was extracted by column chromatography with the eluent (dichloromethane:methanol=97:1.), collected, spun-dried, and observed at . 5), collected and spun dry to give 2-chloro-1,3-benzenediol.