4-Hydroperoxyifosfamide is an anticancer agent that can penetrate the blood-brain barrier (BBB)[1].
References
[1] Ishimoto TM, et al. Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli. Pharmacogenetics. 2002 Oct;12(7):543-53. DOI:10.1097/00008571-200210000-00006