DL-threo-β-Hydroxyaspartic acid (THA) has been used to block glutamate transport in cannulated sprague dawley rat.
L-aspartate beta-carboxylase inhibitor, neurotoxic
A glutamate uptake inhibitor
ChEBI: (3S)-3-hydroxy-L-aspartic acid is the (3S)-diastereomer of 3-hydroxy-L-aspartic acid. It has a role as a metabolite. It is a conjugate acid of a (3S)-3-hydroxy-L-aspartate(2-) and a (3S)-3-hydroxy-L-aspartate(1-). It is an enantiomer of a (3R)-3-hydroxy-D-aspartic acid.
DL-threo-β-hydroxyaspartic acid (THA) is a glutamate uptake inhibitor.