Lodoxamide, which shows some structural similarities to cromolyn and nedocromil, also is a
mast cell stabilizer that inhibits the immediate hypersensitivity reaction, preventing increases
in vascular permeability associated with antigen-IgE–mediated responses. Its precise
mechanism of action is not completely understood. It is used topically in the eye, principally
for conjunctivitis and keratitis associated with vernal allergens.
