Metformin hydrochloride can be used for the following purposes: 1. Type 2 diabetic patients whose condition is not adequately controlled by diet alone (for obese patients and those with hyperinsulinemia, this drug not only lowers blood sugar but also helps reduce weight and alleviate hyperinsulinemia); 2. Certain diabetic patients who respond poorly to sulfonylureas (it can be used in combination with sulfonylureas).
ChEBI: Metformin hydrochloride is a hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride. It has a role as an environmental contaminant, a hypoglycemic agent and a xenobiotic. It contains a metformin(1+).
The boiling mixture of 1,000 L xylene, 450 kg dimethylamine and 840 kg dicyanamide was added 365 kg hydrogene chloride. Yield of biguanide, 1,1- dimethyl-, hydrochloride 1,588 kg (96%). Biguanide, 1,1-dimethyl-, hydrochloride may be recrystallysed from methanol.
