beige to light brown crystalline powder
3-Formylsalicylic acid is a noncompetitive estrone sulfatase inhibitor with an IC50 value of 0.15 mM, a Ki value of 0.12 mM. 3-Formylsalicylic acid shows a low acute toxicity[1].
ChEBI: A hydroxybenzoic acid that is salicylic acid in which the hydrogen at position 3 is substituted by a formyl group.
[1] Jütten P, et al. Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase. J Med Chem. 2007 Jul 26;50(15):3661-6. DOI:
10.1021/jm0611657