DMSO : 100 mg/mL (282.90 mM; ultrasonic and warming and heat to 60°C)
form
Solid
color
White to off-white
Usage And Synthesis
Uses
ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation[1].
