16:0 Phosphatidylbutanol or 1,2-dipalmitoyl-sn-glycero-3-phosphobutanol (sodium salt) has been used to analyze the in vivo activity of phospholipase D (PLD) in Taxus cuspidate using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS).
Phosphatidylbutanol is a low polarity phospholipid, which can be produced by phospholipase D (PLD) specific transphosphatidylation reaction of phosphatidylcholine (PC) and butanol.
Phosphatidylbutanol is used as a biomarker in phospholipase D activity assays.