m-PEG4-sulfonic acid is a PEG linker containing a sulfonic acid group which can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
Uses
m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
