FEM1A (fem-1 homolog A) protein is involved in the regulation of stem-loop binding protein, th at is associated with mRNA cleavage, translation and degradation. FEM1A is involved in anti-inflammatory signaling by interacting with prostaglandin E2 subtype E4 receptors. FEM1A is associated with the pathogenesis of polycystic ovary syndrome. Studies show th at FEM1A gene is downegulated in rhabdomyosarcoma.