[Sar1,Thr8]-Angiotensin II is a potent angiotensin II antagonist. [Sar1,Thr8]-Angiotensin II does not alter cardiac performance. [Sar1,Thr8]-Angiotensin II might be safe for patients with cardiac disease[1].
References
[1] Cody RJ Jr, et al. Hemodynamics of a new angiotensin antagonist, [Sar1, Thr8]A II, in hypertensive man. Circulation. 1980 Feb;61(2):338-44. DOI:10.1161/01.cir.61.2.338