Indatraline (Lu 19005 free base) is a long-acting monoamine reuptake inhibitor that can be used in the research of neurological diseases[1].
ChEBI: (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine is a member of indanes.
Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (K i values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo .
[1] Negus S S, et al. Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys[J]. Journal of Pharmacology and Experimental Therapeutics, 1999, 291(1): 60-69. PMID:10490887