Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2].
| Animal Model: | Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia[2] |
| Dosage: | 0.07 mg/rat |
| Administration: | IV infusion, once |
| Result: | Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight. |