相思豆毒素
相思豆毒素 性质
| 熔点 | >300 °C (dec.)(lit.) |
|---|---|
| 比旋光度 | D21 +44° (0.28 g in 10 ml 0.5N HCl) |
| 沸点 | 358.94°C (rough estimate) |
| 密度 | 1.272±0.06 g/cm3 (20 ºC 760 Torr) |
| 折射率 | 65 ° (C=1, 0.5mol/L NaOH) |
| 储存条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
| 溶解度 | H2O：2 mg/mL（9.16 mM；超声并用 NaOH 将 pH 调节至 10） |
| 形态 | 水晶。 |
| 酸度系数(pKa) | 2.32±0.10(Predicted) |
| 颜色 | 米白色至浅黄色 |
| 旋光度 (Optical Rotation) | [α]20/D +65°, c = 1 in 0.5 M NaOH |
| Merck | 14,10 |
| BRN | 86638 |
| 主要应用 | peptide synthesis |
| InChI | InChI=1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1 |
| InChIKey | CZCIKBSVHDNIDH-NSHDSACASA-N |
| SMILES | C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC |
| CAS 数据库 | 526-31-8(CAS DataBase Reference) |
相思豆毒素 用途与合成方法
L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine.
Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD 50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD 50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 20/21/22 |
| 安全说明 | 36 |
| WGK Germany | 3 |
| 海关编码 | 29339900 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 急性毒性 类别4 经皮 急性毒性 类别4 吸入 急性毒性 类别4 经口 |
相思豆毒素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-12-22 | HY-N1436 | 相思豆毒素 | 526-31-8 | 50 mg | 320 |
| 2025-12-22 | HY-N1436 | 相思豆毒素 | 526-31-8 | 100 mg | 500 |
