Boc-D-Leu-OSu

Boc-D-Leu-OSu is an amino acid-containing building block. It has been used in the synthesis of peptide gastrin antagonists, as well as analogs of the peptide antibiotic gramicidin S.

Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S[1][2].

[1] Rodriguez M, et al. Synthesis of gastrin antagonists, analogues of the C-terminal tetrapeptide of gastrin, by introduction of a beta-homo residue. J Med Chem. 1989 Mar;32(3):522-8. DOI:10.1021/jm00123a003
[2] Sato, et al. Design and Synthesis of Gramicidin S Analogs with High Antibiotic Activity.Bulletin of the Chemical Society of Japan, 2013, 86(1):112-120.